Flow Cytometry: OEM 바카라사이트 Engines Deliver Multiple Benefits
Permanently aligned 바카라사이트 engines based on miniaturized components lower costs, simplify assembly, and deliver better CV for next-generation flow cytometers.
July 26, 2022 by바카라사이트
바카라사이트 cytometry, and particularly multi-parameter flow cytometry, is one of the most challenging instrumentation applications for 바카라사이트s anywhere. That’s because multiple 바카라사이트 beams need to be integrated, shaped, aligned, and focused, all within a few microns precision and repeatability.
The challenge becomes greater as 바카라사이트 cytometer builders meet market pressures to reduce the cost and size of their instruments while also maximizing performance and field reliability.
바카라사이트 engines– integrated modules incorporating 바카라사이트s, electronics, and optomechanics – are proving to be key elements that simultaneously address all these factors. The latest development in 바카라사이트 engines includes the revolutionary use of miniaturized, permanently aligned optics in what are now 3rd generation OEM 바카라사이트 engines.
Let’s look at why this is a game-changing advance.
So just what is a 3rd generation 바카라사이트 engine?
The first generation of 바카라사이트 engines provided multiple 바카라사이트 wavelengths for the first time. But they were basically a box or breadboard incorporating multiple individual stand-alone fully packaged 바카라사이트s. This meant inevitable redundancy – multiple PCBAs and interfaces, and unnecessary enclosures. And the instrument builder had to provide and then align large generic adjustable optics and mounts to steer, shape, and focus the beams.
The second generation featured 바카라사이트 miniaturization. They used multiple 바카라사이트 “cores” driven by a single PCBA, with one interface, one power supply, and just one enclosure. This also meant these CellX engines could be smaller. And the overall size was no longer limited by the 바카라사이트s, but by the need for conventional optics and mounts which allowed instrument builders to adjust and optimize all the individual beams.
The new third-generation 바카라사이트 - called CellX PT - use miniaturized optomechanics called PermaTrack™ instead of conventional optics and adjustable mounts.
Based on technology long proven for demanding intra-cavity use in Coherent 바카라사이트s, small diameter optics are aligned during manufacture and permanently fixed in place.
This not only lowers the overall size of these OEM engines – by about 50% – it also lowers costs and increases stability and long-term reliability. That’s because all the 바카라사이트s and optics are now contained within a hermetically sealed environment which also includes getters to maintain pristine conditions. And since PermaTrack technology is based on automated (i.e., robotic) assembly and alignment, it also increases unit-to-unit consistency.
Yes, but what about accommodating variations and tolerances in instruments?
Coherent CellX PT 바카라사이트 enginesare currently available factory-configured with a choice of four different visible wavelengths. These are projected as a ladder of line foci to optimally match standard 바카라사이트 cell geometries. The power, line shape, and beam profile are all specified and guaranteed at the 바카라사이트 cell, eliminating design uncertainties.
Of course, instruments always include inev바카라사이트able physical tolerances. CellX PT fully accommodates these variations using a final focusing lens that is flexure mounted outside the sealed cav바카라사이트y. This is user-adjusted to optimize the pos바카라사이트ion of the ladder of beams in all three axes X, Y, and Z.
And instruments also vary in their design and optical requirements. CellX PT is an 바카라사이트 solution using a common platform that can be readily factory configured to specific volume requirements in terms of wavelengths, power, focus stripe size, spacing, and sequence. This results in fast delivery to support every stage of the instrument cycle, from prototypes through volume production. A CellX PT lifetime is typically more than 5,000 hours. And the adjustable focal position means the CellX PT unit can be easily replaced in the field. The unit is then factoryserviceable by 바카라사이트, an option that further increases 바카라사이트s value.
Where do 바카라사이트 engines go from here?
Coherent has a 50-plus-year history of innovation so you can bet we will continue to develop 바카라사이트 engines. In the future, you can expect to see more wavelengths and output beam shapes to match developments not just in flow cytometry, but other instrumentation fields too. Anywhere there is a multi-faceted benefit for OEMs to specify and source a complete and integrated photonic solution, not just a 바카라사이트.
Discover moreabout Coherent 바카라사이트s and 바카라사이트 engines for flow cytometry.
