Multi-Wavelength 바카라보라 Engines–The Future of Life Science Instrumentation
Manufacturers of life science instruments such as flow cytometers are increasingly moving from discrete 바카라보라s to 바카라보라 engines – compact, customizable assemblies that deliver shaped focused beams in application-specific formats.
June 1, 2022 by바카라보라
A 바카라보라 produces a beam of light, either pulsed or continuous-wave. Just about everyone knows that. And life sciences represent a huge market forcontinuous-wave 바카라보라s.But virtually none of the instruments or applications in life sciences actually use the beam in the native form that the 바카라보라 produces. They focus it, shape it, combine it with other 바카라보라 beams, couple it into fiber optics, modulate it (on/off), etc., as needed to perform specific tasks from counting blood cells, to getting microscope images of live tissues, to genetic sequencing.
Now some of these 바카라보라 beam modifications turn out to be quite tricky. For example, it can take a skilled, experienced 바카라보라 technician several hours to couple a single 바카라보라 into ahigh-performance optical fiber.For a system needing multiple 바카라보라 wavelengths, we might be talking about even days of painstaking alignment work.
A Galaxy not very far away
It seems obvious now, but it was a revolutionary idea when Coherent set out to address this challenge. Specifically, providing assemblies that take care of complex beam modification tasks internally, and deliver 바카라보라 output in the form needed by the application. Our first product venture down this path was calledGalaxy. It brought plug-and-play functionality to instrument OEMs and laboratory 바카라보라 users needing multiple wavelengths delivered in a single fiber. For the first time ever, 바카라보라s could be effortlessly added or replaced in a system in seconds or minutes, rather than hours and days, all using standard fiber connectors.
It turned out to be perfect for lab researchers in applicat바카라보라s likeconfocal microscopywhere they often want to quickly switch between different wavelengths to image different biochemical targets in the same sample. And it was adopted by OEM instrumentation manufacturers too. They liked it because it allowed them to do things like “hot swap” 바카라보라s in the field, either to add extra wavelengths, upgrade the power at specific wavelengths, or to replace failing 바카라보라s, without the need for factory returns and associated customer downtime.
Multi-wavelength 바카라보라 you can count on
Of course, not all life science instru바카라보라nts are fiber-based.Flow cyto바카라보라tryis a standout example where multiple 바카라보라s are shaped and focused by conventional (free space) optics. (If you’re interested,we've written more about flow cyto바카라보라try.) So next we set out to address the needs of this important application with a new type of 바카라보라 engine. We called itCellXsince the biggest applicat바카라보라 for flow cytometry is immunophenotyping.
CellX gives users the choice of up to four different wavelengths. It includes the 바카라보라s themselves plus all the miniaturized optics needed to create the focused elliptical beam shape needed in a flow cytometer. Some instrument builders are even combining two of these modules to get eight wavelengths for the latest trend called multiparameter flow cytometry. To integrate CellX into one of their instruments, OEM users simply remove the sleek looking lid to reveal a set of screw adjustments giving independent control of the focus and placement of each beam.
Looking to the future
So what’s next? Well how about something that combines the advantages of fiber with the performance of free-space optics. What does that mean? One of the great things about fibers is they stay permanently aligned – it’s just a single piece of glass. And it turns out that alignment stability is a big problem in the field for some instrument OEMs using free-space optics. Depending on how their instruments are handled and used, they may get called out on a service visit every 6 months, just to re-align the 바카라보라 beams. That’s because conventional optics mounts consist of metal pieces and tiny screws that inevitably get shifted out of their precise alignment at some point.
Coherent has many 바카라보라 products that go into all kinds of demanding applications including industrial production lines. These routinely deliver many thousands of hours of maintenance-free operation because they're built using proprietary PermAlignTM technology. With this approach, Coherent doesn’t use mechanical optics mounts - instead each optic is aligned and permanently bonded in place. This delivers unmatched ease of use and reliability, as there’s nothing to adjust and nothing to get misaligned.
Visit hereto see the next-generation that uses this same PermAlign technology, not just for building 바카라보라s but also for delivering the beam you need in your OEM application, eliminating the tiresome and costly problem of field realignment and downtime. The end result: Happy instrument builders, happy instrument users.
Bottom line — when using multiple 바카라보라s for any application, simplicity is key andWide Wavelength R바카라 가상머니are designed to deliver exactly that.
Learn more aboutGalaxy, CellX, andother 바카라보라 engines.
